Description

Repirinast is a selective phosphodiesterase 4 (PDE4) inhibitor with significant anti-inflammatory and anti-allergic properties. This compound is a key intermediate in the synthesis of advanced pharmaceutical actives targeting respiratory and inflammatory conditions. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the development of next-generation therapeutics. The material is supplied to meet the stringent requirements of global regulatory and quality standards.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel PDE4 inhibitor drugs.
• Anti-allergic Drug Research: Used in preclinical and clinical research for developing treatments for asthma, allergic rhinitis, and atopic dermatitis.
• Inflammation Research: Serves as a reference standard and active component in studies targeting chronic inflammatory diseases.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for high-value active pharmaceutical ingredients (APIs).
• Biochemical Tool: Used as a selective PDE4 enzyme inhibitor in biochemical assays and pharmacological studies.

Basic Information

Product Name	Repirinast
CAS No.	73080-51-0
Molecular Formula	C20H21NO5
Molecular Weight	355.39 g/mol
Synonyms	6,7-Dihydro-8-propyl-2-(4-pyridinyl)-4H-pyrazolo[1,5-a][1,3,5]triazin-4-one; MY-5116; Repirinastum; Repirinasto; Repirinast (USAN); 8-Propyl-2-(4-pyridinyl)-6,7-dihydro-4H-pyrazolo[1,5-a][1,3,5]triazin-4-one
EINECS	Contact for details

Quality Control

Our Repirinast is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for advanced intermediates. Specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.