Description

β-Funaltrexamine Hydrochloride is a potent and selective irreversible antagonist of the mu-opioid receptor. This compound is a critical research tool in neuropharmacology for studying opioid receptor function, signaling pathways, and the development of tolerance and dependence. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroscience, pain management, and addiction research.

Application

• Neuroscience Research: Fundamental studies on the role of mu-opioid receptors in the central nervous system.
• Pharmacological Profiling: Used to characterize new chemical entities targeting opioid pathways.
• Mechanism of Action Studies: Investigating opioid tolerance, dependence, and withdrawal mechanisms.
• Pain Research: A key reagent in preclinical models to dissect the components of analgesic pathways.
• Receptor Binding Assays: Serves as a standard or tool compound in competitive binding experiments.
• Academic & Institutional Research: Supporting graduate and postdoctoral research in neuropharmacology.

Basic Information

Product Name	β-Funaltrexamine Hydrochloride
CAS No.	72786-10-8
Molecular Formula	C₂₂H₂₇ClN₂O₄
Molecular Weight	418.91 g/mol
Synonyms	β-Funaltrexamine HCl; β-FNA HCl; 17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxymorphinan-6β-ylamine hydrochloride; Naltrexone derivative; Irreversible mu-opioid antagonist; 6β-Naltrexamine hydrochloride derivative
EINECS	Contact for details

Quality Control

Our β-Funaltrexamine Hydrochloride is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) containing all test results and specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.