Description

5,9-Epoxy-16-Phenoxy-Prostaglandin F1 CAS NO 72657-07-9 is a specialized prostaglandin analog, a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. Its unique epoxy and phenoxy modifications make it a valuable tool for studying prostaglandin receptor activity and metabolic pathways. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents targeting inflammation, ocular pressure, and cardiovascular function.

Application

• Pharmaceutical Intermediate: A key synthetic building block in the research and development of novel prostaglandin-based therapeutics.
• Biochemical Research: Used as a reference standard and probe in studies of prostaglandin receptors (FP, EP receptors) and their signaling mechanisms.
• Ophthalmic Drug Development: Investigated for potential applications in glaucoma treatment due to its structural relation to latanoprost and other FP receptor agonists.
• Inflammation & Immunology Studies: Serves as a tool compound to explore the role of prostaglandin analogs in inflammatory processes and immune modulation.
• Metabolic Pathway Analysis: Employed in research to trace and understand the metabolic fate and stability of modified prostaglandins.

Basic Information

Product Name	5,9-Epoxy-16-Phenoxy-Prostaglandin F1
CAS No.	72657-07-9
Molecular Formula	C₂₇H₃₈O₆
Molecular Weight	458.59 g/mol
Synonyms	16-Phenoxy-5,9-epoxy-17,18,19,20-tetranorprostaglandin F1α; 5,9-Epoxy-16-phenoxy-17,18,19,20-tetranor-PGF1α; 16-Phenoxy-tetranor-PGF1α, 5,9-epoxy-; Prostaglandin F1α analog, 5,9-epoxy-16-phenoxy-; 9,11,15-Trihydroxy-5,9-epoxy-16-phenoxy-17,18,19,20-tetranorprost-13-en-1-oic acid
EINECS	Contact for details

Quality Control

Our 5,9-Epoxy-16-Phenoxy-Prostaglandin F1 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While produced to meet exacting internal standards, specifications can be aligned with specific pharmacopeial or client requirements for advanced development stages.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, maintain in the original sealed vial within a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Any Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.