Description

2(1H)-Pyridinone,3-Fluoro-5-Methyl-(9Ci) is a fluorinated pyridinone derivative, a high-value heterocyclic building block prized for its unique electronic and steric properties. This compound is essential for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of potential drug candidates, particularly kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Investigated as a monomer or functional additive for advanced polymers and electronic materials.
• Chemical Biology: Employed as a probe or tag in biochemical assays and proteomics research due to its distinctive structural motif.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	2(1H)-Pyridinone,3-Fluoro-5-Methyl-(9Ci)
CAS No.	72323-59-2
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	3-Fluoro-5-methylpyridin-2(1H)-one; 3-Fluoro-5-methyl-1H-pyridin-2-one; 3-Fluoro-5-methyl-2(1H)-pyridinone; 5-Methyl-3-fluoro-1H-pyridin-2-one; 3-Fluoro-5-methyl-2-hydroxypyridine; 2-Hydroxy-3-fluoro-5-methylpyridine
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyridinone,3-Fluoro-5-Methyl-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.