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9Alpha, 11, 15S-Trihydroxy-Thromba-5Z, 13E, 17Z-Trien-1-Oic Acid CAS NO 71953-80-5
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CAS No.:71953-80-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
9Alpha, 11, 15S-Trihydroxy-Thromba-5Z, 13E, 17Z-Trien-1-Oic Acid is a high-purity, synthetic prostaglandin analog and a key intermediate in advanced pharmaceutical research and development. This compound is critical for studying and modulating thromboxane and prostaglandin pathways, which are central to numerous physiological and pathological processes. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms focused on cardiovascular, inflammatory, and reproductive health therapeutics.
Application
- Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel prostaglandin-based drugs and active pharmaceutical ingredients (APIs).
- Biochemical Research: Used as a reference standard and tool compound in studies investigating thromboxane receptor activity, signal transduction, and eicosanoid biology.
- Drug Discovery & Development: Employed in high-throughput screening (HTS) and preclinical studies to identify and optimize new therapeutic candidates targeting inflammation, pain, and platelet aggregation.
- Academic Research: Facilitates fundamental research in physiology and pharmacology related to vascular tone, smooth muscle contraction, and inflammatory mediators.
- Analytical Standard: Provides a certified reference material for quality control and method validation in analytical laboratories using techniques like HPLC and LC-MS.
Basic Information
| Item | Details |
|---|---|
| Product Name | 9Alpha, 11, 15S-Trihydroxy-Thromba-5Z, 13E, 17Z-Trien-1-Oic Acid |
| CAS No. | 71953-80-5 |
| Molecular Formula | C20H32O5 |
| Molecular Weight | 352.47 g/mol |
| Synonyms | 9α,11,15S-Trihydroxy-thromba-5Z,13E,17Z-trien-1-oic Acid; Thromboxane B3; TXB3; 9α,11,15-Trihydroxythromba-5,13,17-trien-1-oic Acid; (5Z,9α,11α,13E,15S,17Z)-9,11,15-Trihydroxythromba-5,13,17-trien-1-oic Acid; Prostaglandin H3 metabolite; 11-Dehydro-thromboxane B3 |
| EINECS | Contact for details |
Quality Control
Our 9Alpha, 11, 15S-Trihydroxy-Thromba-5Z, 13E, 17Z-Trien-1-Oic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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