Description

3,5-Difluoropyridine is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for introducing fluorine atoms into complex molecular architectures, directly impacting the potency and metabolic stability of final compounds. This high-purity chemical is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in kinase inhibitors, CNS-active agents, and anti-infectives.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where fluorine substitution enhances biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of fluorinated liquid crystals, organic semiconductors, and polymers with tailored electronic properties.
• Fluorine Chemistry Research: A valuable substrate for studying nucleophilic aromatic substitution and other fluorination-related reactions.

Basic Information

Product Name	3,5-Difluoropyridine
CAS No.	71902-33-5
Molecular Formula	C5H3F2N
Molecular Weight	115.08 g/mol
Synonyms	3,5-Difluoropyridine; Pyridine, 3,5-difluoro-; 3,5-Difluoropyridine (DFP); 3,5-Difluoro-pyridine; 3,5-Difluoropyridin; 3,5-Difluoropyridine, 98+%; 3,5-Difluoropyridine, 99%
EINECS	Contact for details

Quality Control

Our 3,5-Difluoropyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential concentration changes.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.