Description

Prostaglandin E2 Isopropyl Ester is a chemically modified, esterified derivative of the primary prostaglandin E2 (PGE2). This modification enhances its stability and lipophilicity, making it a crucial intermediate and research tool in the synthesis of more complex prostaglandin analogs and pharmaceuticals. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of therapeutics targeting inflammation, reproduction, and cardiovascular function.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the production of advanced prostaglandin-based drugs and prodrugs.
• Biochemical Research: Used in laboratory studies to investigate prostaglandin receptor (EP) signaling pathways and their physiological roles.
• Cell Culture & Differentiation: Employed as a research reagent to study its effects on cell proliferation, differentiation, and apoptosis in various cell lines.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Ophthalmology Research: Investigated for potential applications related to intraocular pressure and ocular inflammation.
• Reproductive Biology Studies: Used in research models to study uterine contractility and cervical ripening mechanisms.

Basic Information

Product Name	Prostaglandin E2 Isopropyl Ester
CAS No.	71845-66-4
Molecular Formula	C23H38O5
Molecular Weight	394.55 g/mol
Synonyms	PGE2 Isopropyl Ester; Dinoprostone Isopropyl Ester; (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid Isopropyl Ester; Isopropyl (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oate; Prostaglandin E2 Isopropyl Ester; PGE2 IPA Ester
EINECS	Contact for details

Quality Control

Our Prostaglandin E2 Isopropyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.