Description

8-Mercaptoriboflavin is a chemically modified derivative of riboflavin (Vitamin B2) where a thiol group replaces a hydroxyl group, creating a unique biochemical probe. This compound matters for its role as a potent inhibitor of flavin-dependent enzymes, making it a critical tool for biochemical research and pharmaceutical development. It is primarily needed by research institutions and pharmaceutical companies engaged in enzymology, metabolic pathway studies, and the development of novel therapeutic agents targeting flavoproteins.

Application

• Biochemical Research: Used as a specific active-site inhibitor to study the mechanism and kinetics of flavin-dependent enzymes such as monoamine oxidases and dehydrogenases.
• Pharmaceutical Development: Serves as a lead compound or molecular scaffold for designing new drugs targeting diseases related to flavoenzyme dysfunction.
• Metabolic Studies: Employed to probe and modulate specific metabolic pathways in cell culture and in vitro systems to understand disease mechanisms.
• Enzyme Assay Development: Utilized in the development and validation of high-throughput screening assays for drug discovery programs.
• Academic Research: A key reagent in university laboratories for fundamental research in biochemistry, molecular biology, and chemical biology.

Basic Information

Product Name	8-Mercaptoriboflavin
CAS No.	71800-64-1
Molecular Formula	C₁₇H₂₀N₄O₆S
Molecular Weight	408.43 g/mol
Synonyms	8-Thioriboflavin; 8-SH-Riboflavin; Riboflavin 8-thiol; Vitamin B2 8-thiol derivative; 7,8-Dimethyl-10-ribitylisoalloxazine-8-thiol; 8-Mercapto-7-methyl-10-((2S,3S,4R)-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione
EINECS	Contact for details

Quality Control

Our 8-Mercaptoriboflavin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality system is designed to meet the exacting standards required for reliable and reproducible scientific research.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.