Description

Cephalomannine CAS NO 71610-00-9 is a bioactive taxane diterpenoid alkaloid, structurally related to paclitaxel, known for its potent cytotoxic properties. This compound is of significant interest for its role in advanced pharmaceutical research and development, particularly in the study of novel anti-cancer mechanisms. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in oncology drug discovery and the synthesis of complex natural product derivatives.

Application

• Pharmaceutical Intermediate: Serves as a key starting material or intermediate in the synthesis of complex anti-cancer agents and novel taxane derivatives.
• Biomedical Research: Used as a reference standard and active compound in in vitro and in vivo studies to investigate apoptosis, microtubule stabilization, and drug resistance mechanisms.
• Oncology Drug Discovery: A critical tool for screening and developing next-generation chemotherapeutic compounds with improved efficacy and reduced side-effect profiles.
• Natural Product Chemistry: Employed in the isolation, purification, and structural analysis of compounds from yew species (Taxus spp.) and other botanical sources.
• Analytical Standard: Provides a high-purity benchmark for quality control and method validation in HPLC, LC-MS, and other analytical techniques within QC laboratories.

Basic Information

Product Name	Cephalomannine
CAS No.	71610-00-9
Molecular Formula	C45H53NO14
Molecular Weight	831.91 g/mol
Synonyms	7-Epi-10-deacetylpaclitaxel; NSC 654735; 5β,20-Epoxy-1,2α,4,7β,10β,13α-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine; Taxane C; Paclitaxel Impurity F
EINECS	Contact for details

Quality Control

Our Cephalomannine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; desiccants are recommended for long-term storage. Keep container tightly sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.