Description

1,1-Dihomo-8-Ketoprostaglandin F1Alpha is a synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of more complex prostaglandin derivatives, which are critical for studying and modulating biological pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of therapeutics targeting inflammation, cardiovascular function, and reproductive health.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel prostaglandin-based drug candidates.
• Biochemical Research: Used as a reference standard or tool compound in studies of eicosanoid signaling pathways and receptor binding assays.
• Prostanoid Synthesis: Serves as a precursor in the multi-step synthesis of specialized pro-resolving mediators (SPMs) and other lipid mediators.
• Academic Research: Employed in university and institutional labs for investigating the physiological and pathological roles of prostaglandin metabolites.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity prostaglandin intermediates.

Basic Information

Product Name	1,1-Dihomo-8-Ketoprostaglandin F1Alpha
CAS No.	71310-81-1
Molecular Formula	C23H38O6
Molecular Weight	410.55 g/mol
Synonyms	1,1-Dihomo-8-keto-PGF1α; 8-Keto-1,1-dihomo-prostaglandin F1α; (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-1,1-dihomoprosta-5,13-dien-8-one; 1,1-Dihomo-8-oxoprostaglandin F1α; Prostaglandin F1α 1,1-dihomo-8-keto derivative; 8-Oxo-1,1-dihomo-PGF1α
EINECS	Contact for details

Quality Control

Our 1,1-Dihomo-8-Ketoprostaglandin F1Alpha is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.