Description

Tyrphostin Ag17 is a potent and selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. This compound is a valuable research-grade chemical tool for studying signal transduction pathways, cellular proliferation, and apoptosis. It is primarily utilized by researchers and scientists in the fields of biochemistry, oncology, and pharmacology for in vitro and cell-based studies.

Application

• Biochemical Research: Used as a selective EGFR tyrosine kinase inhibitor to study enzyme kinetics and signaling mechanisms.
• Cancer Research: Investigated for its effects on tumor cell growth, proliferation, and apoptosis in various cancer cell lines.
• Signal Transduction Studies: A key tool for dissecting the EGFR-mediated pathways involved in cell differentiation and survival.
• Pharmacological Profiling: Employed in high-throughput screening and drug discovery programs targeting tyrosine kinase receptors.
• Academic & Industrial R&D: Serves as a critical reference standard and active compound in university and pharmaceutical R&D laboratories.

Basic Information

Product Name	Tyrphostin Ag17
CAS No.	71308-35-5
Molecular Formula	C16H12N2O3
Molecular Weight	280.28 g/mol
Synonyms	AG 17; AG-17; Tyrphostin AG 17; AG17; 3,4-Dihydroxy-α-cyanocinnamomitrile; RG 50810; RG-50810; EGFR Tyrosine Kinase Inhibitor AG17
EINECS	Contact for details

Quality Control

Our Tyrphostin Ag17 is produced under controlled conditions to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity confirmation and identity verification. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee product integrity and support your research documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.