Description

4-Acetamido-2-Fluoro-5-Methylbenzenesulfonyl Chloride is a high-purity, specialized sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its reactive sulfonyl chloride group and strategically placed acetamido and fluorine substituents, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides where the sulfonyl moiety is a core functional group.
• Dye and Pigment Manufacturing: Serves as an intermediate for creating specialized sulfonated dyes and colorants.
• Material Science Research: Employed in the synthesis of monomers or additives for advanced polymers and functional materials.
• Chemical Biology Probes: Useful for labeling or modifying biomolecules due to its reactive sulfonyl chloride group.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for fine chemical and custom synthesis houses serving diverse R&D sectors.

Basic Information

Product Name	4-Acetamido-2-Fluoro-5-Methylbenzenesulfonyl Chloride
CAS No.	71245-49-3
Molecular Formula	C9H9ClFNO3S
Molecular Weight	265.69 g/mol
Synonyms	N-[5-(Chlorosulfonyl)-2-fluoro-4-methylphenyl]acetamide; 2-Fluoro-5-methyl-4-acetamidobenzenesulfonyl chloride; 4-Acetamido-2-fluoro-5-methylphenylsulfonyl chloride; 4-Acetylamino-2-fluoro-5-methylbenzenesulfonyl chloride; 2-Fluoro-4-acetamido-5-methylbenzenesulfonyl chloride; p-Acetamido-o-fluoro-m-toluenesulfonyl chloride; 71245-49-3; Benzenesulfonyl chloride, 4-(acetylamino)-2-fluoro-5-methyl-
EINECS	Contact for details

Quality Control

Our 4-Acetamido-2-Fluoro-5-Methylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions. Keep away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.