Description

2-Fluoro-5-Iodopyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and cross-coupling reactions, such as Suzuki and Sonogashira couplings.
• Material Science Research: Building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for imaging and diagnostic applications, leveraging the reactivity of the iodine moiety for further functionalization.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for custom synthesis projects requiring specific halogenated pyridine scaffolds.

Basic Information

Item	Detail
Product Name	2-Fluoro-5-Iodopyridine
CAS No.	71197-80-1
Molecular Formula	C5H3F1I1N1
Molecular Weight	222.99 g/mol
Synonyms	5-Iodo-2-fluoropyridine; 2-Fluoro-5-iodopyridine; 5-Iodo-2-fluoro-pyridine; Pyridine, 2-fluoro-5-iodo-; 2-Fluoropyridin-5-yl iodide; 2-Fluoro-5-iodo-pyridine; 2-F-5-I-Pyridine; 5-I-2-F-Pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Iodopyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with each shipment to guarantee compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.