Description

[2-Hydroxy-1,1-Bis(Hydroxymethyl)Ethyl]Ammonium 7-[3,5-Dihydroxy-2-[3-Hydroxy-4-(3-Thienyloxy)But-1-Enyl]Cyclopentyl]Hept-5-Enoate is a high-purity synthetic intermediate of significant pharmaceutical interest. This compound matters as a key building block in the synthesis of complex prostaglandin analogs and other bioactive molecules, offering a critical pathway for advanced research and development. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing novel therapeutics in areas such as ophthalmology and inflammation.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmic Drug Research: Used in the development of prostaglandin analogs for treating glaucoma and ocular hypertension.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the creation of new chemical entities.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of high-value, complex organic molecules.
• Biochemical Research: Utilized in studies investigating prostaglandin receptors and signaling pathways.

Basic Information

Item	Detail
Product Name	[2-Hydroxy-1,1-Bis(Hydroxymethyl)Ethyl]Ammonium 7-[3,5-Dihydroxy-2-[3-Hydroxy-4-(3-Thienyloxy)But-1-Enyl]Cyclopentyl]Hept-5-Enoate
CAS No.	71116-83-1
Molecular Formula	C24H39NO9S
Molecular Weight	517.63 g/mol
Synonyms	Travoprost Ammonium Salt; Travoprost Tromethamine; AL-6221; AL 6221; 7-[3,5-Dihydroxy-2-[3-Hydroxy-4-(3-thienyloxy)-1-butenyl]cyclopentyl]-5-heptenoic Acid 2-Hydroxy-1,1-bis(hydroxymethyl)ethylammonium Salt; (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-Hydroxy-4-(3-thienyloxy)-1-buten-1-yl]cyclopentyl]-5-Heptenoic Acid Compound with 2-Amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
EINECS	Contact for details

Quality Control

Our [2-Hydroxy-1,1-Bis(Hydroxymethyl)Ethyl]Ammonium 7-[3,5-Dihydroxy-2-[3-Hydroxy-4-(3-Thienyloxy)But-1-Enyl]Cyclopentyl]Hept-5-Enoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is light-sensitive and easily oxidized; it should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.