Description

1,3-Benzenediamine, 4-Methyl-, Labeled With Tritium is a specialized radiolabeled derivative of 4-methyl-m-phenylenediamine, where tritium (³H) atoms are incorporated into the molecular structure. This compound is a critical tool in pharmaceutical and biochemical research, enabling precise tracking and quantification of metabolic pathways, binding affinities, and distribution studies. It is primarily utilized by research scientists and process development teams in the pharmaceutical, agrochemical, and life science sectors for advanced analytical applications.

Application

• Tracer Studies in Drug Metabolism and Pharmacokinetics (DMPK): Used to investigate the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities.
• Receptor Binding Assays: Essential for studying ligand-receptor interactions and determining binding constants in neurological and pharmacological research.
• Metabolic Pathway Analysis: Enables the elucidation of biochemical pathways in both mammalian and microbial systems.
• Environmental Fate Studies: Applied in agrochemical research to trace the degradation and environmental persistence of compounds.
• Autoradiography and Imaging: Serves as a radiolabel for histological and whole-body imaging techniques to visualize compound localization.
• Quality Control for Radiolabeled Compounds: Acts as a reference standard in the synthesis and purification of other tritiated materials.

Basic Information

Product Name	1,3-Benzenediamine, 4-Methyl-, Labeled With Tritium
CAS No.	71111-07-4
Molecular Formula	C7H10N2 (³H labeled)
Molecular Weight	~122.17 g/mol (varies with specific activity)
Synonyms	4-Methyl-m-phenylenediamine, Tritiated; [³H]-4-Methyl-1,3-benzenediamine; 2,4-Diaminotoluene, Tritiated; 4-Methyl-1,3-phenylenediamine-³H; Toluene-2,4-diamine, Labeled with Tritium; 2,4-Toluenediamine-³H; 4-Methyl-m-phenylenediamine (³H); m-Toluenediamine, Tritiated
EINECS	Contact for details

Quality Control

Every batch of our radiolabeled compounds is produced and analyzed under strict quality protocols. Certificates of Analysis (COA) are provided, detailing key parameters such as radiochemical purity (typically >97% by HPLC), specific activity, and chemical purity. Our quality systems ensure traceability and compliance with relevant GLP (Good Laboratory Practice) standards for research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated, appropriately shielded freezer for radioactive materials. This product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere if specified. Follow all local and international regulations for the storage and handling of radioactive substances.

Specification

Item	Specification
Appearance	Solution in specified solvent (e.g., Ethanol)
Identification (HPLC)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Customizable (e.g., 10-80 Ci/mmol)
Chemical Purity (HPLC)	≥ 98%
Solvent	Ethanol or as specified
Concentration	1.0 mCi/mL (or as customized)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.