Description

Pinane Thromboxane A2 is a stable, bicyclic analog of the potent pro-thrombotic and vasoconstrictive eicosanoid, Thromboxane A2. This compound is a critical pharmacological research tool and a key intermediate in the synthesis of thromboxane receptor antagonists and other bioactive molecules. It is essential for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors, particularly those focused on cardiovascular disease, thrombosis, and inflammation.

Application

• Pharmacological Research: Used as a stable reference standard and agonist in studies of thromboxane receptor (TP receptor) signaling and function.
• Drug Discovery & Development: Serves as a key synthetic intermediate and a structural template for designing novel thromboxane synthase inhibitors and receptor antagonists.
• Biochemical Assays: Employed in in vitro and cell-based assays to study platelet aggregation, vasoconstriction, and related pathological pathways.
• Reference Standard: Provides a high-purity benchmark for analytical method development and validation in quality control laboratories.
• Academic Research: Facilitates fundamental studies in eicosanoid biology, signal transduction, and the molecular mechanisms of hemostasis.

Basic Information

Product Name	Pinane Thromboxane A2
CAS No.	71111-01-8
Molecular Formula	C21H34O5
Molecular Weight	366.50 g/mol
Synonyms	9,11-Epoxy-15-hydroxy-13-pinaneprosta-5,13-dien-1-oic acid; Pinane TXA2; (5Z,9α,11α,13E,15S)-9,11-Epoxy-15-hydroxythromboxa-5,13-dien-1-oic acid, Pinane Derivative; STA2 (Pinane analog); Thromboxane A2 Pinane Analog; PTXA2
EINECS	Contact for details

Quality Control

Our Pinane Thromboxane A2 is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis and structural confirmation (NMR, MS). A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.