Description

1,1,1-Trifluoro-3-(6-Methylpyridin-2-Yl)Propan-2-One is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl ketone moiety adjacent to a heterocyclic system makes it a versatile intermediate for creating compounds with enhanced metabolic stability and bioavailability. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in developing new-generation herbicides and insecticides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Fluorine Chemistry: An essential substrate for studying fluorine introduction and its effects on molecular properties in medicinal chemistry programs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for investigating biological pathways and protein interactions.

Basic Information

Product Name	1,1,1-Trifluoro-3-(6-Methylpyridin-2-Yl)Propan-2-One
CAS No.	71046-13-4
Molecular Formula	C9H8F3NO
Molecular Weight	203.16 g/mol
Synonyms	2-Propanone, 1,1,1-trifluoro-3-(6-methyl-2-pyridinyl)-; 1,1,1-Trifluoro-3-(6-methyl-2-pyridyl)propan-2-one; 3-(6-Methylpyridin-2-yl)-1,1,1-trifluoropropan-2-one; 6-Methyl-2-(3,3,3-trifluoro-2-oxopropyl)pyridine; 2-Acetyl-3,3,3-trifluoropropyl 6-methylpyridine; TFMP Ketone Derivative
EINECS	Contact for details

Quality Control

Every batch of 1,1,1-Trifluoro-3-(6-Methylpyridin-2-Yl)Propan-2-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.