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N2-[N2-(3-Hydroxy-9-Methyl-1-Oxodecyl)-D-Dab-]Cyclo[L-Dab*-L-Dab-D-Leu-L-Phe-L-Dab-L-Dab-L-Leu-] CAS NO 71043-99-7
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CAS No.:71043-99-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
N2-[N2-(3-Hydroxy-9-Methyl-1-Oxodecyl)-D-Dab-]Cyclo[L-Dab*-L-Dab-D-Leu-L-Phe-L-Dab-L-Dab-L-Leu-] is a complex, synthetic cyclic peptide derivative, also known as a lipopeptide antibiotic precursor. This compound is of significant interest in advanced pharmaceutical research and development due to its intricate structure, which is designed to mimic or interfere with natural biological processes. It serves as a critical intermediate or reference standard for the synthesis and study of novel antimicrobial agents, particularly those targeting resistant bacterial strains. Key industries that require this high-purity specialty chemical include pharmaceutical R&D, biotechnology, and academic research institutions focused on developing next-generation therapeutics.
Application
- Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel lipopeptide antibiotics and other peptide-based therapeutic agents.
- Research & Development: Used as a reference standard or lead compound in biochemical and microbiological research to study structure-activity relationships (SAR) and mechanism of action.
- Antimicrobial Agent Development: Investigated for its potential activity against drug-resistant bacteria, including Gram-positive pathogens like MRSA (Methicillin-resistant *Staphylococcus aureus*).
- Bioconjugation Studies: Utilized in the development of targeted drug delivery systems due to its peptide backbone and functional groups suitable for conjugation.
- Academic Research: Employed in university and institutional labs for advanced studies in medicinal chemistry, peptide synthesis, and antibiotic discovery.
- Quality Control & Analytical Standards: Acts as a high-purity certified reference material (CRM) for analytical method development and validation in QC laboratories.
Basic Information
| Item | Detail |
|---|---|
| Product Name | N2-[N2-(3-Hydroxy-9-Methyl-1-Oxodecyl)-D-Dab-]Cyclo[L-Dab*-L-Dab-D-Leu-L-Phe-L-Dab-L-Dab-L-Leu-] |
| CAS No. | 71043-99-7 |
| Molecular Formula | C58H98N12O12 |
| Molecular Weight | 1131.5 g/mol |
| Synonyms | Cyclic Lipopeptide Antibiotic Intermediate; [D-Dab1, L-Dab2, L-Dab5, L-Dab6, D-Leu3, L-Phe4, L-Leu7]cyclo-peptide derivative; 3-Hydroxy-9-methyl-1-oxodecyl-D-Dab-cyclo(L-Dab-L-Dab-D-Leu-L-Phe-L-Dab-L-Dab-L-Leu); Lipopeptide precursor 71043-99-7; Antibiotic core structure; Synthetic cyclic peptide; Contact for additional synonyms. |
| EINECS | Contact for details |
Quality Control
Our production of N2-[N2-(3-Hydroxy-9-Methyl-1-Oxodecyl)-D-Dab-]Cyclo[L-Dab*-L-Dab-D-Leu-L-Phe-L-Dab-L-Dab-L-Leu-] adheres to stringent quality management protocols suitable for research and pharmaceutical-grade materials. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and NMR for structural verification. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal quality standards. Our commitment is to supply high-purity, well-characterized reference materials to support critical R&D and preclinical studies.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent degradation. For short-term use, the material may be kept at 2-8°C. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC-MS) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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