Description

D-[1-13C]Xylose is a stable isotope-labeled analog of the pentose sugar D-xylose, where the carbon-1 position is enriched with the non-radioactive 13C isotope. This compound is an essential tracer in metabolic research, enabling precise tracking of carbohydrate metabolism and flux analysis in biological systems. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic manufacturers for advanced studies in metabolism, biomarker discovery, and the development of clinical diagnostic tests.

Application

• Metabolic Pathway Tracing: Used as a 13C-labeled tracer in in vitro and in vivo studies to elucidate the pentose phosphate pathway and other carbohydrate metabolic routes.
• Biomarker Research: Employed in the development and validation of clinical breath tests, such as those for small intestinal bacterial overgrowth (SIBO) and malabsorption syndromes.
• Pharmaceutical R&D: Serves as a critical tool in drug metabolism and pharmacokinetics (DMPK) studies to understand how new therapeutics affect sugar metabolism.
• Nutritional Science: Applied in research to investigate glucose metabolism, insulin resistance, and the metabolic effects of different diets.
• Stable Isotope Labeling: Acts as a building block for the synthesis of more complex 13C-labeled compounds for use in NMR and mass spectrometry.
• Microbial Metabolism Studies: Used to study carbohydrate utilization and fermentation pathways in various microorganisms.

Basic Information

Product Name	D-[1-13C]Xylose
CAS No.	70849-21-7
Molecular Formula	C413CH10O5
Molecular Weight	151.12 g/mol (for 13C1 isotopologue)
Synonyms	(1-13C)-D-Xylose; D-Xylose-1-13C; [1-13C]Xylose; Xylose (D-13C1); Wood Sugar-1-13C; (1-13C)Xylopyranose; 70849-21-7; Aldopentose-1-13C
EINECS	Contact for details

Quality Control

Our D-[1-13C]Xylose is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and LC-MS, to confirm isotopic enrichment, chemical purity, and identity. Certificates of Analysis (COA) detailing isotopic purity (atom % 13C), chemical purity, and specific tests are provided with every shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Isotopic Purity (Atom % 13C)	≥ 99%
Chemical Purity (HPLC)	≥ 98%
Specific Optical Rotation	+18.5° to +19.5° (c=10 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.