Description

Phthalic Acid (Carboxyl-13C) is a stable isotope-labeled derivative of phthalic acid, where the carbon atom in the carboxyl group is the carbon-13 (13C) isotope. This compound is essential as a high-purity internal standard and tracer in quantitative analytical techniques, enabling precise measurement and method validation. It is primarily required by research institutions, pharmaceutical developers, and analytical laboratories engaged in advanced mass spectrometry (MS), nuclear magnetic resonance (NMR) spectroscopy, and metabolic pathway studies.

Application

• Quantitative Analytical Internal Standard: Used in LC-MS and GC-MS for the accurate quantification of phthalic acid, phthalate esters, and related metabolites in complex matrices.
• Metabolic Tracer Studies: Employed in 13C-labeling experiments to investigate metabolic fluxes, degradation pathways, and the environmental fate of phthalates.
• NMR Spectroscopy Reference: Serves as a chemical shift reference and a tool for elucidating molecular structures and dynamics in solution.
• Pharmaceutical Research & Development: Critical for drug metabolism and pharmacokinetics (DMPK) studies to track the absorption, distribution, metabolism, and excretion (ADME) of phthalate-containing compounds.
• Environmental Analysis: Enhances the accuracy of detecting and quantifying trace levels of phthalate plasticizers and their breakdown products in environmental samples.
• Quality Control & Method Development: Used to develop, validate, and ensure the precision of analytical methods in compliance with Good Laboratory Practice (GLP) and other regulatory guidelines.

Basic Information

Product Name	Phthalic Acid (Carboxyl-13C)
CAS No.	70838-83-4
Molecular Formula	C7H413CO4 or C7H4O4 (13C1)
Molecular Weight	167.10 g/mol (for 13C1 labeled form)
Synonyms	1,2-Benzenedicarboxylic-13C acid; Benzene-1,2-dicarboxylic-13C acid; 13C1-Phthalic Acid; o-Phthalic Acid-13C (carboxyl); Isotope Labeled Phthalic Acid; Carbon-13 Labeled Phthalic Acid; Phthalic-13C Acid; ISOTOPICALLY LABELED PHTHALIC ACID
EINECS	Contact for details

Quality Control

Our Phthalic Acid (Carboxyl-13C) is manufactured under controlled conditions to ensure exceptional isotopic and chemical purity, meeting the stringent requirements of research and analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity, and identity confirmation via spectroscopic methods. We adhere to relevant quality standards to ensure batch-to-batch consistency and reliability for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent absorption of atmospheric moisture, which could affect stability and analytical performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.