Description

2-Methylbenzoic Acid-13C1 (Carboxyl-13C) is a stable isotope-labeled analog of o-toluic acid, where the carbon atom in the carboxyl group is enriched with the 13C isotope. This precise isotopic labeling is critical for applications requiring high sensitivity and accurate quantification, such as mass spectrometry-based analysis. It is an essential tool for researchers and analytical scientists in pharmaceutical development, environmental testing, and metabolic studies who require reliable internal standards for precise trace analysis.

Application

• Used as an internal standard in quantitative mass spectrometry (LC-MS, GC-MS) for the accurate measurement of o-toluic acid and related compounds.
• Essential in pharmaceutical research for drug metabolism and pharmacokinetic (DMPK) studies to track the fate of drug molecules.
• Applied in environmental analysis for the detection and quantification of aromatic acid pollutants in complex matrices.
• Utilized in isotope dilution analysis to achieve superior accuracy in analytical chemistry methods.
• Serves as a key building block in the synthesis of 13C-labeled complex molecules for advanced research applications.
• Supports clinical diagnostics and biomarker discovery by enabling precise measurement of metabolic pathways.

Basic Information

Product Name	2-Methylbenzoic Acid-13C1 (Carboxyl-13C)
CAS No.	70838-82-3
Molecular Formula	C7H713COOH
Molecular Weight	138.14 (for 13C1 labeled form)
Synonyms	o-Toluic Acid-13C1 (carboxyl); 2-Methyl-13C-benzoic Acid; 2-Toluic Acid-13C1; (2-Methylphenyl)-13C-methanoic Acid; o-Methylbenzoic Acid-13C1; 1-Carboxy-2-methylbenzene-13C1; 2-Carboxytoluene-13C1
EINECS	Contact for details

Quality Control

Our 2-Methylbenzoic Acid-13C1 (Carboxyl-13C) is produced under strict quality management systems to ensure the highest isotopic and chemical purity. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >99 atom % 13C), chemical purity (by HPLC), and identity confirmation (by NMR and IR). We adhere to relevant industry standards to support GLP and GMP compliant research.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. The product is stable under these conditions for extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
13C Isotopic Enrichment	≥99 atom %
Chemical Purity (Titration)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.