Description

trans-Tranilast is a synthetic derivative of N-(3,4-dimethoxycinnamoyl) anthranilic acid, known for its potent anti-allergic and anti-fibrotic properties. This compound is a critical active pharmaceutical ingredient (API) and a valuable research chemical for investigating inflammatory pathways. It is primarily utilized by pharmaceutical manufacturers and life science research organizations. The product is supplied as a high-purity material to meet the stringent requirements of drug development and advanced biochemical studies.

Application

• Active Pharmaceutical Ingredient (API) in anti-allergic and anti-asthmatic medications.
• Key intermediate in the synthesis of novel pharmaceutical compounds targeting fibrosis and inflammation.
• Reference standard for quality control and analytical method development in pharmaceutical laboratories.
• Biochemical research tool for studying mast cell stabilization and TGF-β (Transforming Growth Factor-beta) inhibition.
• Raw material for the development of topical formulations for dermatological conditions like keloids and hypertrophic scars.
• Starting material for the preparation of metabolites and derivatives for pharmacological profiling.

Basic Information

Item	Detail
Product Name	trans-Tranilast
CAS No.	70806-55-2
Molecular Formula	C18H17NO5
Molecular Weight	327.33 g/mol
Synonyms	N-(3,4-Dimethoxycinnamoyl)anthranilic Acid; Tranilast (trans-isomer); Rizaben; N-5'; KCA-098; N-(3',4'-Dimethoxycinnamoyl)anthranilic Acid; 2-[[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]amino]benzoic acid
EINECS	Contact for details

Quality Control

Our trans-Tranilast is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for identification, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with relevant standards for pharmaceutical intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.