Description

27-De(2-Amino-3-Methyl-1-Oxobutyl)Boromycin is a structurally modified derivative of the polyketide macrolide antibiotic boromycin. This compound is of significant interest in research and development for its potential biological activities and as a key intermediate in synthetic chemistry. It is primarily utilized by pharmaceutical researchers, medicinal chemists, and biotechnology firms engaged in the discovery of novel antimicrobial agents and the study of ionophore properties. The product is supplied with a CAS Number of 70658-70-7.

Application

• Pharmaceutical Research: Serves as a critical intermediate in the synthesis and structural modification of boromycin-derived antibiotics to explore new therapeutic avenues.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to understand the impact of specific functional group modifications on biological potency and selectivity.
• Antimicrobial Agent Development: Investigated for its potential antibacterial and antifungal properties against resistant strains.
• Ionophore Research: Studied for its ability to transport ions across lipid membranes, relevant in biochemical and biophysical research.
• Chemical Biology: Employed as a molecular probe to study biological pathways and target interactions.
• Reference Standard: Used as an analytical standard in quality control laboratories for the identification and quantification of related compounds.

Basic Information

Product Name	27-De(2-Amino-3-Methyl-1-Oxobutyl)Boromycin
CAS No.	70658-70-7
Molecular Formula	C42H68BNO15
Molecular Weight	837.80 g/mol
Synonyms	27-De(2-Amino-3-methylbutanoyl)boromycin; Boromycin derivative; 27-De(2-Amino-3-methyl-1-oxobutyl)boromycin; 70658-70-7; Boromycin, 27-de(2-amino-3-methyl-1-oxobutyl)-; (2R,3S,4S,5S,6R)-5-[(3S,5S,7S,9S,10S,12S,13R,14S,15R)-14-[(2R,5S,6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]oxy-15-hydroxy-2,10,12-trimethyl-9-[(2S)-1-methylpropyl]-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-3-yl]oxy-6-methyl-2-(2-methylpropyl)oxane-3,4-diol
EINECS	Contact for details

Quality Control

Our 27-De(2-Amino-3-Methyl-1-Oxobutyl)Boromycin is produced under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.