Description

Aflatrem CAS NO 70553-75-2 is a potent tremorgenic mycotoxin produced by certain strains of *Aspergillus* fungi. This compound is of significant interest in biochemical and pharmacological research due to its specific neurotoxic activity, which induces sustained tremors. It serves as a critical reference standard and research tool for scientists in toxicology, mycology, and neuroscience, enabling the study of mycotoxin mechanisms, food safety analysis, and neurological pathway investigation.

Application

• Analytical Reference Standard: Primary use as a high-purity certified standard for the accurate quantification and identification of aflatrem in complex matrices via HPLC, LC-MS, or GC-MS.
• Toxicology Research: Essential for studying the mechanisms of tremorgenic mycotoxins, their metabolic pathways, and their acute and chronic effects in biological systems.
• Food & Feed Safety Analysis: Used in the development and validation of analytical methods to screen for and confirm the presence of aflatrem in agricultural commodities, ensuring regulatory compliance and safety.
• Neuroscience Studies: A valuable tool for investigating neurotoxic syndromes, studying tremor induction, and exploring impacts on the central nervous system in model organisms.
• Mycological & Fungal Metabolism Studies: Employed in research focused on fungal secondary metabolism, the conditions that promote mycotoxin production, and strategies for fungal control.
• Pharmaceutical Research: Used in exploratory studies to understand toxin-receptor interactions, which can inform the development of novel therapeutic agents or antidotes.

Basic Information

Product Name	Aflatrem
CAS No.	70553-75-2
Molecular Formula	C₃₂H₃₉NO₆
Molecular Weight	533.66 g/mol
Synonyms	Aflatrem; NSC 339586; Tremorgenic mycotoxin aflatrem; Aspertoxin; 6a,12a-Epoxy-7,9,11-trimethoxy-2,3,6a,12a-tetrahydro-6H-furo[2,3-h]furo[3',2':4,5]furo[2,3-h]chromen-6-one; (6aR,12aR)-6a,12a-Epoxy-7,9,11-trimethoxy-2,3,6a,12a-tetrahydro-6H-furo[2,3-h]furo[3',2':4,5]furo[2,3-h]chromen-6-one
EINECS	Contact for details

Quality Control

Our Aflatrem is produced and handled under strict quality management protocols to ensure the highest standards of purity and consistency for research applications. Each batch is subjected to comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. A Certificate of Analysis (COA) detailing batch-specific results is provided, ensuring full traceability and reliability for your critical research and analytical work.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.