Description

Phorbol 12-Monoacetate, 4Beta is a specific, acetylated derivative of the phorbol diterpene family, known for its potent biological activity. This compound serves as a critical reference standard and research tool in biochemical and pharmacological studies. It is primarily utilized by researchers in the life sciences, pharmaceutical development, and toxicology sectors for investigating cellular signaling pathways and protein kinase C (PKC) activation mechanisms.

Application

• Biomedical Research: As a high-purity reference standard for calibrating analytical instruments and validating experimental assays.
• Pharmacology & Toxicology: Used in studies to understand the mechanisms of tumor promotion and PKC modulation.
• Drug Discovery: Employed as a biochemical tool to screen for potential inhibitors of PKC-related pathways.
• Academic Research: Fundamental research in cell biology, signal transduction, and cancer biology.
• Standards & Metrology: Serves as a certified reference material (CRM) for quality control in analytical laboratories.

Basic Information

Product Name	Phorbol 12-Monoacetate, 4Beta
CAS No.	70470-59-6
Molecular Formula	C24H32O7
Molecular Weight	432.51 g/mol
Synonyms	4β-Phorbol 12-Acetate; 12-O-Acetylphorbol; 4β-Phorbol 12-Monoacetate; Phorbol 12-Acetate; NSC 406042; 12-Acetylphorbol; TPA (partial synonym, often refers to 12-O-Tetradecanoylphorbol-13-acetate); 4β,9α,20-Trihydroxy-1,6-tiglia-trien-3-one 12-acetate
EINECS	Contact for details

Quality Control

Our Phorbol 12-Monoacetate, 4Beta is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for reference materials to support your compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is light-sensitive (store away from light). For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.