Description

2,5-Dibromobenzotrifluoride is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine substituents and a trifluoromethyl group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the bromine atoms enable further functionalization.
• Material Science Research: Acts as a monomer or building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry: The presence of the trifluoromethyl group makes it valuable for introducing fluorine into target molecules to modulate bioavailability and metabolic stability.

Basic Information

Product Name	2,5-Dibromobenzotrifluoride
CAS No.	7657-09-2
Molecular Formula	C7H3Br2F3
Molecular Weight	313.90 g/mol
Synonyms	1,4-Dibromo-2-(trifluoromethyl)benzene; 2,5-Dibromo-α,α,α-trifluorotoluene; 2,5-Dibromobenzotrifluoride; 2-(Trifluoromethyl)-1,4-dibromobenzene; Benzene, 1,4-dibromo-2-(trifluoromethyl)-; α,α,α-Trifluoro-2,5-dibromotoluene
EINECS	Contact for details

Quality Control

Our 2,5-Dibromobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.