Description

Benzene-1,3-Disulfonyl Fluoride is a versatile and highly reactive aromatic sulfonyl fluoride derivative. This compound serves as a critical bifunctional building block in advanced organic synthesis, enabling the precise introduction of sulfonyl fluoride groups into target molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs and bioactive molecules via sulfur(VI) fluoride exchange (SuFEx) click chemistry.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require the sulfonyl fluoride pharmacophore.
• Polymer & Materials Science: Acts as a cross-linking agent or functional monomer for producing specialty polymers, coatings, and high-performance materials with tailored properties.
• Chemical Biology & Proteomics: Employed as an activity-based probe (ABP) for labeling and studying serine hydrolases and other enzymes.
• Ligand & Catalyst Development: Useful for synthesizing novel ligands and organocatalysts containing sulfonyl fluoride motifs.
• Organic Synthesis Building Block: Provides a handle for further functionalization to create complex, disubstituted benzene derivatives.

Basic Information

Product Name	Benzene-1,3-Disulfonyl Fluoride
CAS No.	7552-55-8
Molecular Formula	C6H4F2O4S2
Molecular Weight	242.22 g/mol
Synonyms	1,3-Benzenedisulfonyl Fluoride; m-Benzenedisulfonyl Fluoride; Benzene-1,3-bis(sulfonyl Fluoride); 1,3-Bis(fluorosulfonyl)benzene; m-Phenylene Disulfonyl Fluoride; 3-Fluorosulfonylbenzenesulfonyl Fluoride; m-Disulfonylfluorobenzene; EINECS 231-447-1
EINECS	231-447-1

Quality Control

Our Benzene-1,3-Disulfonyl Fluoride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are kept sealed to minimize exposure to atmospheric moisture and light to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.