Description

4-(N,N-Dimethyl)Anilinemagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, widely used in advanced organic synthesis. Its core value lies in its ability to act as a powerful nucleophile and base, facilitating the formation of carbon-carbon bonds essential for constructing complex molecular architectures. This compound is particularly critical for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries engaged in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing the 4-(dimethylamino)phenyl moiety into target molecules, a common pharmacophore in drug discovery.
• Agrochemical Production: Used in the synthesis of advanced herbicides, fungicides, and plant growth regulators requiring specific aryl-amine structures.
• Fine Chemical & Dye Manufacturing: Employed in the production of complex organic dyes, pigments, and photoinitiators where precise aromatic substitution is necessary.
• Material Science Research: Serves as a precursor for creating functionalized monomers and ligands used in polymer and catalyst development.
• Cross-Coupling Reactions: Acts as an efficient coupling partner in transition metal-catalyzed reactions, such as Kumada couplings, to form biaryl structures.
• Nucleophilic Addition to Carbonyls: Used for the addition to aldehydes, ketones, and esters to synthesize tertiary alcohols and related derivatives.

Basic Information

Product Name	4-(N,N-Dimethyl)Anilinemagnesium Bromide
CAS No.	7353-91-5
Molecular Formula	C8H11BrMgN
Molecular Weight	225.39 g/mol
Synonyms	4-(Dimethylamino)phenylmagnesium bromide; p-(Dimethylamino)phenylmagnesium bromide; N,N-Dimethyl-4-bromomagnesioaniline; Grignard reagent of 4-bromo-N,N-dimethylaniline; (4-(Dimethylamino)phenyl)magnesium bromide; Magnesium, bromo[4-(dimethylamino)phenyl]-; 4-Bromo-N,N-dimethylaniline magnesium derivative; p-Dimethylaminophenylmagnesium bromide
EINECS	Contact for details

Quality Control

Our 4-(N,N-Dimethyl)Anilinemagnesium Bromide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Quality is assured through comprehensive analytical testing, including titration for assay determination and spectroscopic methods for identity confirmation. A Certificate of Analysis (COA) detailing purity, concentration (typically supplied as a solution in THF or diethyl ether), and relevant parameters is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its nature as a highly volatile and easily oxidized Grignard reagent, it must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions. The container should be kept in a cool, dry, well-ventilated place away from moisture, heat, and incompatible materials such as acids, oxidizing agents, and protic solvents.

Specification

Item	Specification
Appearance	Solution (typically in THF or Et2O), color may vary from brown to gray
Identification (IR)	Conforms to structure
Assay (Titration)	0.5 M to 2.0 M in solvent (or as specified)
Purity (GC/HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.