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3β-[(2-o-Acetyl-6-Deoxy-3-o-Methyl-α-L-Glucopyranosyl)Oxy]-11α,12α-Epoxy-14-Hydroxy-5β-Card-20(22)-Enolide CAS NO 7227-00-1


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CAS No.:7227-00-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3β-[(2-o-Acetyl-6-Deoxy-3-o-Methyl-α-L-Glucopyranosyl)Oxy]-11α,12α-Epoxy-14-Hydroxy-5β-Card-20(22)-Enolide is a high-purity, structurally complex cardiac glycoside derivative. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the study of cardiac pharmacology and the synthesis of novel therapeutic agents. It serves as a critical intermediate or reference standard for researchers and manufacturers in the pharmaceutical and biotechnology sectors.

Application

  • Pharmaceutical Intermediate: A key building block for the synthesis of novel cardiac glycosides and related therapeutic compounds.
  • Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related drug substances.
  • Biochemical Research: Employed in pharmacological studies to investigate mechanisms of action related to sodium-potassium ATPase inhibition.
  • Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the research and development of potential new cardiovascular drugs.
  • Academic Research: Utilized in university and institutional labs for studies in medicinal chemistry and natural product derivatives.

Basic Information

Product Name 3β-[(2-o-Acetyl-6-Deoxy-3-o-Methyl-α-L-Glucopyranosyl)Oxy]-11α,12α-Epoxy-14-Hydroxy-5β-Card-20(22)-Enolide
CAS No. 7227-00-1
Molecular Formula C32H46O11
Molecular Weight 606.71 g/mol
Synonyms 3β-[(2-O-Acetyl-6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-11α,12α-epoxy-14-hydroxy-5β-card-20(22)-enolide; 3β-[(2-O-Acetyl-6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-11α,12α-epoxy-5β-card-20(22)-enolide; Strophanthidin 3-(2-acetyl-6-deoxy-3-methyl-α-L-glucoside), 11α,12α-epoxide; 11α,12α-Epoxystrophanthidin 3-(2-acetyl-6-deoxy-3-methyl-α-L-glucoside); A derivative of Convallatoxin; Contact for details on additional trade names.
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Quality Control

Our 3β-[(2-o-Acetyl-6-Deoxy-3-o-Methyl-α-L-Glucopyranosyl)Oxy]-11α,12α-Epoxy-14-Hydroxy-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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