Description

Lincomycin Hydrochloride Monohydrate is a monohydrated hydrochloride salt form of the lincosamide antibiotic lincomycin. This compound is a critical active pharmaceutical ingredient (API) valued for its potent activity against Gram-positive bacteria, particularly anaerobic organisms. It is primarily utilized in the pharmaceutical industry for the formulation of injectable and topical antibiotic preparations. The product is supplied as a high-purity material suitable for GMP manufacturing processes.

Application

• Active Pharmaceutical Ingredient (API) in injectable antibiotic formulations.
• Key component in topical ointments, creams, and gels for skin infections.
• Veterinary pharmaceutical applications for treating bacterial infections in animals.
• Research and development of new antibacterial agents and combination therapies.
• Manufacturing of reference standards for quality control laboratories.
• Intermediate in the synthesis of more complex semi-synthetic lincosamide antibiotics.

Basic Information

Product Name	Lincomycin Hydrochloride Monohydrate
CAS No.	7179-49-9
Molecular Formula	C18H34N2O6S • HCl • H2O
Molecular Weight	461.01 g/mol
Synonyms	Lincomycin HCl Monohydrate; Lincomycin Hydrochloride Hydrate; U-10149A; Lincocin (brand/trade name); (2S,4R)-N-[(1R,2R)-2-Hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide hydrochloride monohydrate; Lincolnensin; Cillinicina.
EINECS	Contact for details

Quality Control

Our Lincomycin Hydrochloride Monohydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. Specifications are aligned with major pharmacopoeial guidelines. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	3.0% - 5.0%
pH (1% solution)	3.0 - 5.5
Specific Rotation	+137° to +145°
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 0.25 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.