Description

4-(Propionylamino)Benzenesulfonyl Chloride (Saltdata: Free) is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile intermediate for introducing the sulfonamide functional group, enabling the creation of complex molecules with targeted biological or material properties. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including diuretics, carbonic anhydrase inhibitors, and antibacterial agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that utilize the sulfonamide moiety for bioactivity.
• Dye and Pigment Manufacturing: Serves as an intermediate for producing sulfonated azo dyes and other colorants with enhanced solubility and fastness properties.
• Polymer Science: Employed in the creation of specialty polymers and resins, where it can act as a cross-linking agent or to introduce sulfonamide groups for modified material characteristics.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Ligand and Catalyst Preparation: Useful in the synthesis of specialized ligands for metal catalysis or in the preparation of organocatalysts.

Basic Information

Product Name	4-(Propionylamino)Benzenesulfonyl Chloride (Saltdata: Free)
CAS No.	7139-88-0
Molecular Formula	C9H10ClNO3S
Molecular Weight	247.70 g/mol
Synonyms	4-(Propionamido)benzenesulfonyl chloride; N-(4-Sulfonylchloridophenyl)propionamide; p-(Propionylamino)benzenesulfonyl chloride; 4-Propionamidobenzenesulfonyl chloride; Benzenesulfonyl chloride, 4-[(1-oxopropyl)amino]-; NSC 403107; 4-Propionylaminobenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-(Propionylamino)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.