Description

1-Fluoro-4-(Methoxymethyl)Benzene is a versatile fluorinated aromatic building block with a reactive methoxymethyl side chain. This compound matters for its dual functionality, offering sites for both electrophilic aromatic substitution and ether cleavage or modification, making it a valuable intermediate in complex organic synthesis. It is needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials industries for constructing active molecules and functional polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances bioactivity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display and lighting technologies.
• Polymer Chemistry: Acts as a monomer or modifying agent for introducing aromatic fluorine and ether functionalities into specialty polymers.
• Cross-Coupling Reactions: A suitable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for method development and as a versatile building block in multi-step syntheses.

Basic Information

Product Name	1-Fluoro-4-(Methoxymethyl)Benzene
CAS No.	7116-50-9
Molecular Formula	C9H11FO
Molecular Weight	154.18 g/mol
Synonyms	4-Fluorobenzyl Methyl Ether; (4-Fluorophenyl)methoxymethane; 1-Fluoro-4-methoxymethylbenzene; p-Fluorobenzyl Methyl Ether; 4-(Methoxymethyl)fluorobenzene; α-Methoxy-4-fluorotoluene; 4-Fluoro-α-methoxytoluene
EINECS	Contact for details

Quality Control

Our 1-Fluoro-4-(Methoxymethyl)Benzene is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of fine chemical and pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.4850 - 1.4950
Density (20°C)	1.05 - 1.15 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.