Description

(Chlorofluoromethyl)Benzene is a versatile halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both chlorine and fluorine atoms on a reactive benzyl position, makes it a valuable precursor for introducing functionalized benzyl groups into target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the chlorofluoromethyl moiety imparts specific biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays.
• Polymer Modification Agent: Employed to introduce functional benzyl groups into polymer chains, altering material properties.
• Cross-coupling Reactions: Acts as an electrophile in various palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Organic Synthesis Reagent: A versatile reagent for nucleophilic substitution reactions, enabling the introduction of diverse functionalities.

Basic Information

Product Name	(Chlorofluoromethyl)Benzene
CAS No.	7111-89-9
Molecular Formula	C7H6ClF
Molecular Weight	144.57 g/mol
Synonyms	α-Chloro-α-fluorotoluene; Benzyl Chloride, α-fluoro-; (Chlorofluoromethyl)benzene; 1-(Chlorofluoromethyl)benzene; Fluorochloromethylbenzene; α-Fluoro-α-chlorotoluene; (Fluorochloromethyl)benzene; Toluene, α-chloro-α-fluoro-
EINECS	Contact for details

Quality Control

Our (Chlorofluoromethyl)Benzene is produced under stringent quality management protocols. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the exacting requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to guarantee traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.18 g/cm³
Boiling Point	~ 185-190 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.