Description

3,3,4,4,4-Pentafluoro-1-Butyne is a highly fluorinated alkyne building block, valued for its unique reactivity profile and ability to introduce pentafluorobutyl groups into target molecules. This compound is essential for advanced organic synthesis, particularly in the development of novel fluorinated materials and active pharmaceutical ingredients (APIs). It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to enhance product properties through selective fluorination.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced fluorinated pesticides and herbicides for enhanced efficacy and environmental profile.
• Material Science: Precursor for creating specialty fluoropolymers, surface modifiers, and liquid crystals with unique thermal and chemical resistance.
• Organic Synthesis: Versatile reagent for introducing the pentafluorobutyl moiety via click chemistry, Sonogashira coupling, and other cross-coupling reactions.
• Fluorinated Surfactant & Lubricant Development: Serves as a starting material for synthesizing high-performance fluorosurfactants and lubricants.
• Research & Development: Critical tool for medicinal chemistry and material science R&D exploring the effects of specific fluorination patterns.

Basic Information

Item	Detail
Product Name	3,3,4,4,4-Pentafluoro-1-Butyne
CAS No.	7096-51-7
Molecular Formula	C4HF5
Molecular Weight	144.04 g/mol
Synonyms	Pentafluorobut-1-yne; 1-Butyne, 3,3,4,4,4-pentafluoro-; 3,3,4,4,4-Pentafluorobutyne; Pentafluorobut-1-yne; 3,3,4,4,4-Pentafluoro-1-butyne; Pentafluorobutylacetylene; 1-Pentafluorobut-1-yne
EINECS	Contact for details

Quality Control

Our 3,3,4,4,4-Pentafluoro-1-Butyne is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, preferably at 2-8°C. Keep away from heat, sparks, and open flames. The container must be kept tightly sealed in an upright position to prevent leakage and pressure build-up.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.