Description

Phlorizin Dihydrate is a high-purity dihydrate form of the natural phenolic compound, phlorizin, identified by CAS NO 7061-54-3. This compound is a critical reference standard and active ingredient valued for its specific biological activity as a potent, competitive inhibitor of sodium-glucose linked transporters (SGLTs). It is primarily sought by research institutions and manufacturers in the pharmaceutical, nutraceutical, and life science sectors for applications in metabolic disorder research, drug discovery, and the development of analytical methods.

Application

• Pharmaceutical Research & Development: As a key reference standard and pharmacological tool for studying glucose metabolism, diabetes, and renal function via SGLT inhibition.
• Biochemical Assay Development: Used in the design and validation of in vitro screening assays for SGLT1 and SGLT2 activity.
• Academic & Preclinical Studies: Employed in metabolic research to investigate mechanisms of action, pharmacokinetics, and potential therapeutic applications.
• Nutraceutical Formulation: A potential ingredient in advanced dietary supplements targeting blood sugar management, subject to regulatory approval.
• Analytical Chemistry: Serves as a primary standard for the quantitative analysis of phlorizin and related compounds using HPLC, LC-MS, or other chromatographic techniques.
• Cosmeceutical Research: Investigated for potential skin-related benefits due to its antioxidant and bioactive properties.

Basic Information

Product Name	Phlorizin Dihydrate
CAS No.	7061-54-3
Molecular Formula	C21H24O10 · 2H2O
Molecular Weight	472.44 g/mol (Dihydrate)
Synonyms	Phloridzin Dihydrate; Phloretin 2'-β-D-glucoside Dihydrate; 1-[2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone Dihydrate; NSC 407292; Floridzin; Phlorhizin; Apple peel extract constituent; SGLT Inhibitor.
EINECS	Contact for details

Quality Control

Our Phlorizin Dihydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing specific results for assay, related substances, and residual solvents is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent absorption of water vapor.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	6.5% - 8.5% (Theoretical for dihydrate: ~7.6%)
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.