Description

18-Hydroxy-11-Dehydrotetrahydrocorticosterone is a key steroid intermediate and metabolite of corticosterone. This compound is of significant value in pharmaceutical research and development, particularly in the study of adrenal steroidogenesis and metabolic pathways. It serves as a critical reference standard and building block for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of steroid metabolites in research and quality control laboratories.
• Biochemical Research: A vital tool in endocrinology studies for investigating corticosteroid biosynthesis, metabolism, and related enzyme activities.
• Metabolite Synthesis: Serves as a key synthetic intermediate or precursor in the preparation of more complex steroid derivatives and labeled compounds.
• Diagnostic Development: Employed in the development and calibration of diagnostic assays, such as LC-MS/MS methods, for measuring steroid hormone levels.
• Academic Research: Utilized in university and institutional labs for fundamental studies in steroid chemistry and physiology.

Basic Information

Product Name	18-Hydroxy-11-Dehydrotetrahydrocorticosterone
CAS No.	7050-24-0
Molecular Formula	C21H32O5
Molecular Weight	364.48 g/mol
Synonyms	18-Hydroxy-11-dehydrotetrahydrocorticosterone; 18-Hydroxy-11-dehydro-THB; 5β-Pregnane-3α,18,21-triol-11,20-dione; 18,21-Dihydroxy-5β-pregnane-3,11,20-trione; 18-Hydroxy-11-dehydrotetrahydro compound B; 18-OH-11-dehydro-THB; 18-Hydroxy-11-dehydrocorticosterone metabolite; Tetrahydro-11-dehydrocorticosterone 18-ol
EINECS	Contact for details

Quality Control

Our 18-Hydroxy-11-Dehydrotetrahydrocorticosterone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.