Description

17,18-Dehydroprostaglandin E1 is a synthetic prostaglandin analog, a key intermediate in the research and development of novel pharmaceutical compounds. Its value lies in its specific structural modification, which allows scientists to study structure-activity relationships and develop targeted therapeutic agents. This high-purity biochemical is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors, particularly those focused on cardiovascular, inflammatory, and metabolic drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced prostaglandin-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies to investigate prostaglandin receptor activity and signaling pathways.
• Drug Discovery & Development: Employed in high-throughput screening (HTS) and medicinal chemistry programs to develop new therapies for conditions like hypertension, thrombosis, and inflammation.
• Academic Research: Serves as a key reagent in university and institutional labs for studying eicosanoid biology, vascular function, and cellular regulation.
• Analytical Standard: Used for method development, calibration, and quality control in analytical laboratories (HPLC, LC-MS) to ensure accuracy in prostaglandin analysis.

Basic Information

Product Name	17,18-Dehydroprostaglandin E1
CAS No.	7046-45-9
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	17,18-Didehydroprostaglandin E1; PGE1 (17,18-Dehydro); (5Z,13E)-(15S)-9α,11α,15-Trihydroxy-17,18-didehydroprosta-5,13-dien-1-oic Acid; 17,18-Dehydro-PGE1; δ¹⁷,¹⁸-Prostaglandin E1; 17(18)-Dehydroprostaglandin E1
EINECS	Contact for details

Quality Control

Our 17,18-Dehydroprostaglandin E1 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, desiccate to protect against moisture. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.