Description

2,3-Dinor Prostaglandin E1 is a key metabolite and analog of Prostaglandin E1 (Alprostadil), playing a significant role in the study of eicosanoid metabolism and vascular biology. This compound is valued for its utility as a reference standard and a critical intermediate in advanced pharmaceutical research and development. It is primarily needed by research institutions, pharmaceutical companies, and diagnostic manufacturers focused on cardiovascular research, metabolic studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of prostaglandin metabolites in research and quality control laboratories.
• Biochemical Research: Serves as a crucial tool in studying eicosanoid pathways, vascular tone regulation, and platelet aggregation mechanisms.
• Metabolite Analysis: Employed in clinical and preclinical studies to trace the metabolic fate of administered Prostaglandin E1 (Alprostadil).
• Diagnostic Development: Acts as a calibrator or antigen in the development of immunoassays for prostaglandin-related biomarkers.
• Organic Synthesis Intermediate: Utilized as a building block for the synthesis of more complex prostaglandin analogs and derivatives for pharmacological evaluation.

Basic Information

Product Name	2,3-Dinor Prostaglandin E1
CAS No.	7046-40-4
Molecular Formula	C18H30O5
Molecular Weight	326.43 g/mol
Synonyms	2,3-Dinor PGE1; Dinoprostone Metabolite; (5Z,13E)-(9S,11R,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic Acid; 2,3-Dinorprostaglandin E1; PGEM-I; 13,14-Dihydro-15-keto-2,3-dinor-PGE1; Alprostadil Metabolite
EINECS	Contact for details

Quality Control

Every batch of our 2,3-Dinor Prostaglandin E1 is manufactured and analyzed under strict quality management systems. We employ advanced analytical techniques, including HPLC and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.