Description

2-Bromo-5-Fluorobenzene-1-Sulfonyl Chloride is a high-purity, multi-functional aromatic sulfonyl chloride building block essential for advanced organic synthesis. This compound is valued for its dual reactive sites, enabling precise molecular construction in complex chemical pathways. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, leveraging the fluorine and bromine substituents for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of specialized polymers and advanced functional materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation, labeling proteins, or creating activity-based probes for enzyme studies.
• Dye & Pigment Manufacturing: Employed in the synthesis of complex organic dyes and pigments, where the sulfonyl chloride group facilitates attachment to other aromatic systems.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences industry with tailored molecular entities.

Basic Information

Product Name	2-Bromo-5-Fluorobenzene-1-Sulfonyl Chloride
CAS No.	771-67-5
Molecular Formula	C6H3BrClFO2S
Molecular Weight	273.51 g/mol
Synonyms	2-Bromo-5-fluorobenzenesulfonyl chloride; 5-Fluoro-2-bromobenzenesulfonyl chloride; 1-Bromo-4-fluoro-2-sulfonylchloridobenzene; Benzenesulfonyl chloride, 2-bromo-5-fluoro-; 2-Bromo-5-fluorophenylsulfonyl chloride; 771-67-5; 2-Br-5-F-PhSO2Cl
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Fluorobenzene-1-Sulfonyl Chloride is produced and tested under a strict quality management system. We guarantee high chemical purity and consistency, with comprehensive testing including assay, identity confirmation, and impurity profiling. A Certificate of Analysis (COA) documenting all critical parameters is provided with each shipment to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.