Description

5-Bromo-2-Fluoropyridine is a versatile halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce key functional groups and modulate the biological activity of target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced metabolic stability and bioavailability.
• Ligand and Catalyst Development: Used to create specialized pyridine-based ligands for transition metal catalysis in fine chemical manufacturing.
• Material Science Research: Intermediate in the production of organic electronic materials, such as charge-transport layers or light-emitting components.
• Cross-Coupling Reactions: Serves as a reliable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Fluorinated Compound Libraries: Essential for medicinal chemistry programs focused on creating fluorinated compound libraries to explore structure-activity relationships (SAR).

Basic Information

Product Name	5-Bromo-2-Fluoropyridine
CAS No.	766-11-0
Molecular Formula	C5H3BrFN
Molecular Weight	175.99 g/mol
Synonyms	2-Fluoro-5-bromopyridine; 5-Bromo-2-fluoropyridine; 2-Fluoro-5-bromo-pyridine; 5-Bromo-2-fluoro-pyridine; 766-11-0; Pyridine, 5-bromo-2-fluoro-; NSC 403058
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.