Description

Ethanesulfonic Acid Fluoride is a highly reactive organosulfur compound primarily used as a key fluorinating and sulfonylating agent in advanced chemical synthesis. Its value lies in its ability to efficiently introduce the ethanesulfonyl fluoride moiety, a crucial building block for creating sulfonamides and other functionalized molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of sulfonamide-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with sulfonyl fluoride functional groups.
• Chemical Research & Development: Serves as a versatile building block for constructing complex molecules in medicinal and organic chemistry.
• Polymer Modification: Employed to introduce sulfonyl fluoride groups into polymers for creating functional materials with specific properties.
• Proteomics & Bioconjugation: Acts as a reactive handle in chemical biology for labeling proteins and studying protein function (SuFEx chemistry).
• Material Science: Used in the development of advanced coatings, membranes, and other specialty materials.

Basic Information

Product Name	Ethanesulfonic Acid Fluoride
CAS No.	754-03-0
Molecular Formula	C2H5FO2S
Molecular Weight	112.12 g/mol
Synonyms	Ethanesulfonyl Fluoride; Ethylsulfonyl Fluoride; 1-Fluoroethanesulfonic Acid; ESF; Sulfurofluoridic Acid, Ethyl Ester; NSC 88266; Ethanesulfonic Acid, Fluoride
EINECS	212-038-8

Quality Control

Our Ethanesulfonic Acid Fluoride is produced under stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including assay, purity verification, and impurity profiling, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed and stored at temperatures recommended on the Safety Data Sheet (typically 2-8°C or as specified).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC)	≤ 1.0% (total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.