Description

Prostaglandin F3Alpha CAS NO 745-64-2 is a bioactive lipid compound belonging to the prostaglandin family, specifically a fluorinated analog of Prostaglandin F2α. This compound is of significant interest in advanced pharmaceutical research and development due to its potent biological activity and structural specificity. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in the development of novel therapeutics, particularly in the fields of ophthalmology, reproductive medicine, and metabolic studies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates targeting prostaglandin receptors.
• Ophthalmic Research: Used in preclinical studies to investigate intraocular pressure regulation and develop treatments for conditions like glaucoma.
• Reproductive Biology Studies: Applied in research concerning luteolysis and the regulation of reproductive cycles in animal models.
• Biochemical Standard: Acts as a high-purity reference standard for analytical method development and validation in bioanalytical laboratories.
• Cell Signaling Research: Employed to study FP receptor-mediated signaling pathways and their role in various physiological and pathological processes.
• Veterinary Pharmaceutical Development: Investigated for potential applications in animal health, particularly in estrus synchronization.

Basic Information

Product Name	Prostaglandin F3Alpha
CAS No.	745-64-2
Molecular Formula	C₂₀H₃₁FO₅
Molecular Weight	370.46 g/mol
Synonyms	PGF3α; 9α,11α,15α-Trihydroxy-5-cis-13-trans-prostadienoic Acid; Fluprostenol (related analog); 17-Phenyltrinor Prostaglandin F2α Fluorinated Analog; (5Z,13E)-(9S,11R,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic Acid (fluorinated derivative); Prostaglandin F2α 3-Trifluoromethyl Analog; 16-Fluoro Prostaglandin F2α
EINECS	Contact for details

Quality Control

Our Prostaglandin F3Alpha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (typically ≥95% by area normalization), to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay, related substances, and residual solvents. We adhere to cGMP guidelines where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is light-sensitive and easily oxidized; therefore, it should be handled in a controlled environment and allowed to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.