Description

Prostaglandin F1Alpha is a primary prostaglandin, a member of the F-series, that serves as a fundamental bioactive lipid mediator. It is a critical reference standard and intermediate in biochemical research and pharmaceutical development. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors focusing on prostaglandin pathways, inflammation studies, and the synthesis of more complex therapeutic agents.

Application

• Biochemical Research: Used as a primary standard and reference material in studies of prostaglandin biosynthesis, metabolism, and receptor interactions.
• Pharmaceutical Intermediates: Serves as a key starting material or intermediate in the synthesis of more complex prostaglandin analogs and derivatives for therapeutic use.
• Cell Signaling Studies: Applied in in vitro and in vivo research to investigate the role of prostaglandins in physiological and pathological processes, such as inflammation and smooth muscle contraction.
• Analytical Method Development: Utilized as a certified reference material (CRM) for calibrating analytical instruments and validating methods like HPLC and LC-MS in quality control laboratories.
• Enzyme Activity Assays: Employed as a substrate or product in enzymatic assays to study the activity of cyclooxygenases (COX) and other enzymes in the eicosanoid pathway.

Basic Information

Product Name	Prostaglandin F1Alpha
CAS No.	745-62-0
Molecular Formula	C₂₀H₃₄O₅
Molecular Weight	354.48 g/mol
Synonyms	PGF1α; 9α,11α,15S-Trihydroxyprosta-5Z,13E-dien-1-oic acid; (5Z,13E,15S,9α,11α)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid; Prostaglandin F1α; 9,11,15-Trihydroxyprosta-5,13-dienoic acid
EINECS	Contact for details

Quality Control

Our Prostaglandin F1Alpha is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to industry best practices for high-purity biochemicals, ensuring material integrity from synthesis to shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.