Description

4'-Trifluoromethylphenyl Acetylene is a high-purity, versatile aromatic acetylene derivative characterized by its trifluoromethyl functional group. This compound is a critical building block in advanced organic synthesis, offering unique electronic properties that facilitate the creation of complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of compounds with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group can improve biological activity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions to construct conjugated systems.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable reagent for studying the effects of fluorine substitution on reaction pathways and material properties in academic and industrial R&D.

Basic Information

Product Name	4'-Trifluoromethylphenyl Acetylene
CAS No.	705-31-7
Molecular Formula	C9H5F3
Molecular Weight	170.13 g/mol
Synonyms	1-Ethynyl-4-(trifluoromethyl)benzene; 4-Ethynylbenzotrifluoride; (4-Trifluoromethylphenyl)acetylene; 4-(Trifluoromethyl)phenylacetylene; p-Trifluoromethylphenylacetylene; α-(Trifluoromethyl)phenylacetylene; 4-CF3-Phenylacetylene
EINECS	Contact for details

Quality Control

Our 4'-Trifluoromethylphenyl Acetylene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider under an inert atmosphere such as nitrogen or argon to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.