Description

2,3,5,6-Tetrafluoro-p-Xylene is a highly fluorinated aromatic compound, serving as a critical building block in advanced material synthesis. Its unique structure, featuring four fluorine atoms on the aromatic ring, provides exceptional chemical stability and specific reactivity, making it invaluable for creating high-performance polymers and specialty chemicals. This intermediate is essential for R&D and production in the pharmaceutical, agrochemical, and advanced electronics industries, where precise fluorination is required to modify material properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, high-efficacy fluorinated pesticides and herbicides.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials.
• Polymer & Resin Modification: Incorporated into specialty polymers, such as polyimides and epoxy resins, to enhance thermal stability, chemical resistance, and dielectric properties.
• Fluorinated Surfactants & Coatings: A precursor for synthesizing surfactants and surface treatment agents with low surface energy and high durability.
• Organic Synthesis & Catalysis: Employed as a versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis.

Basic Information

Product Name	2,3,5,6-Tetrafluoro-p-Xylene
CAS No.	703-87-7
Molecular Formula	C8H4F4
Molecular Weight	176.11 g/mol
Synonyms	1,2,4,5-Tetrafluoro-3,6-dimethylbenzene; 2,3,5,6-Tetrafluoro-1,4-dimethylbenzene; p-Xylene, 2,3,5,6-tetrafluoro-; 3,6-Dimethyl-1,2,4,5-tetrafluorobenzene; Tetrafluoro-p-xylene; TFX; α,α,α',α'-Tetrafluoro-p-xylene
EINECS	211-867-5

Quality Control

Our 2,3,5,6-Tetrafluoro-p-Xylene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Melting Point	95 - 98 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.