Description

3-Fluorobenzenesulfonyl Chloride is a key fluorinated aromatic sulfonyl chloride derivative, serving as a versatile and reactive building block in advanced organic synthesis. Its primary value lies in introducing the 3-fluorobenzenesulfonyl moiety, a crucial pharmacophore and structural motif in modern chemical development. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, enabling the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of sulfonamide-based drug candidates, including kinase inhibitors, receptor antagonists, and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers, resins, and functional coatings.
• Chemical Research: A valuable reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Manufacturing: Employed in the synthesis of fluorinated dyes and pigments for advanced optical applications.

Basic Information

Product Name	3-Fluorobenzenesulfonyl Chloride
CAS No.	701-27-9
Molecular Formula	C6H4ClFO2S
Molecular Weight	194.61 g/mol
Synonyms	m-Fluorobenzenesulfonyl Chloride; 3-Fluorophenylsulfonyl Chloride; Benzenesulfonyl chloride, 3-fluoro-; 1-Fluoro-3-(chlorosulfonyl)benzene; 3-Fluorobenzene-1-sulfonyl chloride; m-Fluorophenylsulfonyl chloride; 3-FBSCl
EINECS	211-861-6

Quality Control

Our 3-Fluorobenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.