Description

5-Fluoronicotinamide is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique structure, which introduces both fluorine and an amide functional group, enabling precise modifications to molecular frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals. The product is supplied under stringent quality control to ensure batch-to-batch consistency for demanding R&D and production applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity, stability, and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for constructing specialized ligands in catalytic systems or as a component in metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers or organic electronic materials that require fluorinated aromatic units.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags or other molecular probes for biochemical research.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific fluorinated nicotinamide derivatives.

Basic Information

Product Name	5-Fluoronicotinamide
CAS No.	70-58-6
Molecular Formula	C6H5FN2O
Molecular Weight	140.12 g/mol
Synonyms	5-Fluoropyridine-3-carboxamide; 3-Carbamoyl-5-fluoropyridine; 5-Fluoro-3-pyridinecarboxamide; Nicotinamide, 5-fluoro-; 5-Fluoronicotinic acid amide; 5-Fluoro-3-pyridylcarboxamide; 5-Fluoronicotinamide (70-58-6)
EINECS	Contact for details

Quality Control

Our 5-Fluoronicotinamide is manufactured under a quality management system to ensure high purity and reliability. Each batch undergoes rigorous analytical testing, including HPLC for assay and purity determination. Certificates of Analysis (COA) detailing specific results for identity, purity, and related substances are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.