Description

Pax2 Inhibitor Eg1 (CAS NO 693241-54-2) is a potent and selective small molecule inhibitor of the Pax2 transcription factor, a key regulator in developmental pathways and cellular differentiation. This compound is a critical research tool for investigating the role of Pax2 in organogenesis, tissue repair, and its implications in various disease states, including certain cancers and renal disorders. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in molecular biology, oncology research, and drug discovery programs.

Application

• Biomedical Research: Fundamental tool for studying Pax2-mediated signaling pathways in developmental biology and disease models.
• Oncology Research: Investigation of Pax2's role in tumor progression, metastasis, and as a potential therapeutic target in cancers where it is overexpressed.
• Nephrology Studies: Research into kidney development, regeneration, and polycystic kidney disease mechanisms.
• Neuroscience: Exploration of Pax2 function in neural development and the central nervous system.
• Drug Discovery: Used as a reference compound or lead molecule in high-throughput screening and structure-activity relationship (SAR) studies for novel Pax2 inhibitors.
• Cell Biology Assays: Application in in vitro and cell-based assays to modulate gene expression and study downstream effects.

Basic Information

Product Name	Pax2 Inhibitor Eg1
CAS No.	693241-54-2
Molecular Formula	C₂₀H₂₀N₄O₃
Molecular Weight	364.40 g/mol
Synonyms	Eg1; Pax2 Inhibitor; 2-[(4-Methylphenyl)sulfonyl]-5-(1H-pyrrol-1-yl)-1H-benzimidazole; 2-(4-Methylphenyl)sulfonyl-5-(1H-pyrrol-1-yl)-1H-benzimidazole; Benzimidazole, 2-[(4-methylphenyl)sulfonyl]-5-(1H-pyrrol-1-yl)-; TOCRIS-3724; CAS 693241-54-2
EINECS	Contact for details

Quality Control

Our Pax2 Inhibitor Eg1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Specifications are designed to meet the rigorous demands of pharmaceutical and academic research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.