Description

3-(2,6-Difluorophenyl)Benzaldehyde is a high-purity fluorinated aromatic aldehyde building block, identified by CAS number 691905-33-6. This compound is a critical intermediate valued for its unique difluorophenyl substitution pattern, which imparts desirable electronic and steric properties for advanced synthesis. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluorophenyl moiety enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where fluorinated aromatics tune electronic properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-(2,6-Difluorophenyl)Benzaldehyde
CAS No.	691905-33-6
Molecular Formula	C13H8F2O
Molecular Weight	218.20 g/mol
Synonyms	3-(2,6-Difluorophenyl)benzaldehyde; [1,1'-Biphenyl]-3-carboxaldehyde, 2',6'-difluoro-; 2',6'-Difluoro[1,1'-biphenyl]-3-carboxaldehyde; Benzaldehyde, 3-(2,6-difluorophenyl)-; 3-(2,6-Difluorophenyl)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-(2,6-Difluorophenyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality commitment supports compliance with cGMP, ICH guidelines, and relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.