Description

4-(2-Fluorophenyl) Piperidine Hydrochloride is a high-purity, pharmaceutically relevant organic salt used as a critical building block in advanced chemical synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific fluorinated piperidine structure is essential. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and psychiatric therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its fluorinated aromatic and piperidine motifs.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Industrial R&D: Utilized in exploratory organic synthesis for creating new chemical entities with potential biological activity.

Basic Information

Product Name	4-(2-Fluorophenyl) Piperidine Hydrochloride
CAS No.	691875-81-7
Molecular Formula	C11H15ClFN
Molecular Weight	215.70 g/mol
Synonyms	4-(2-Fluorophenyl)piperidine hydrochloride; 4-(2-Fluorophenyl)piperidine HCl; 2-Fluoro-4-piperidinylbenzene hydrochloride; 1-(2-Fluorophenyl)-4-piperidinol hydrochloride (tautomer); Piperidine, 4-(2-fluorophenyl)-, hydrochloride; 691875-81-7; 4-(o-Fluorophenyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(2-Fluorophenyl) Piperidine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.